Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Rheumatoid nodules
- Radiologic Findings
- The initial posteroanterior chest radiograph shows no abrnoaml finding. Follow up chest radiograph obatained 10 months later shows nodular lesions in both mid lateral lung zones. On chest CT, multiple small nodules are seen along the pleura and fissure in both hemithoraces. PET/CT images show multiple mild to moderate hypermetabolic lesions in bilateral subpleural areas (SUV range 1~4). Thoracoscopic surgery revealed thickening of the visceral pleura with multiple hard whitish nodules. Pathologic diagnosis was fibrinoid necrosis surrounded by epithelioid macrophages and chronic inflammation, granuloma with central necrosis, suggestive of rheumatoid nodules.
- Brief Review
- Rheumatoid (necrobiotic) nodules are an uncommon manifestation of rheumatoid arthritis. They often are asymptomatic but tend to appear and disappear in conjunction with subcutaneous nodules. They range in size from a few millimeters to 5 cm or more and may be solitary or multiple and numerous. Rheumatoid nodules predominate in the lung periphery and typically are well defined. They may cavitate, having thick walls that eventually become thin with healing. Pleural effusion may be associated. The cavitary nodules in the periphery may lead to pneumothorax.
- Please refer to
Case 879, Case 798, -
- References
- Keywords
- Lung, Connective tissue diseases,